Position 123 of halohydrin dehalogenase HheG plays an important role in stability, activity, and enantioselectivity-Reference-Cited by-同舟云学术

Position 123 of halohydrin dehalogenase HheG plays an important role in stability, activity, and enantioselectivity

Published:2019-03-25 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Solarczek Jennifer,Klünemann Thomas,Brandt Felix^ORCID,Schrepfer Patrick,Wolter Mario^ORCID,Jacob Christoph R.^ORCID,Blankenfeldt Wulf^ORCID,Schallmey Anett^ORCID

Funder

Deutsche Forschungsgemeinschaft

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-41498-2.pdf

Reference45 articles.

1. Schallmey, A. & Schallmey, M. Recent advances on halohydrin dehalogenases: from enzyme identification to novel biocatalytic applications. Appl. Microbiol. Biotechnol. 100, 7827–7839 (2016).

2. Hasnaoui-Dijoux, G., Majeric Elenkov, M., Lutje Spelberg, J. H., Hauer, B. & Janssen, D. B. Catalytic promiscuity of halohydrin dehalogenase and its application in enantioselective epoxide ring opening. ChemBioChem 9, 1048–1051 (2008).

3. Fox, R. J. et al. Improving catalytic function by ProSAR-driven enzyme evolution. Nat. Biotechnol. 25, 338–344 (2007).

4. Ma, S. K. et al. A green-by-design biocatalytic process for atorvastatin intermediate. Green Chem. 12, 81–86 (2010).

5. Wan, N.-W. et al. An efficient high-throughput screening assay for rapid directed evolution of halohydrin dehalogenase for preparation of β-substituted alcohols. Appl. Microbiol. Biotechnol. 99, 4019–4029 (2015).

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2. Performance of cross‐linked enzyme crystals of engineered halohydrin dehalogenase HheG in different chemical reactor systems;Biotechnology and Bioengineering;2023-08-18

3. Impact of organic solvents on the catalytic performance of halohydrin dehalogenase;Applied Microbiology and Biotechnology;2023-03-07

4. Crystal Contact Engineering for Enhanced Cross-Linking Efficiency of HheG Crystals;Catalysts;2022-12-01

5. G‐type Halohydrin Dehalogenases Catalyze Ring Opening Reactions of Cyclic Epoxides with Diverse Anionic Nucleophiles**;Chemistry – A European Journal;2022-11-14