Secreted IgM deficiency leads to increased BCR signaling that results in abnormal splenic B cell development
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-03688-8.pdf
Reference31 articles.
1. Ehrenstein, M. R. & Notley, C. A. The importance of natural IgM: scavenger, protector and regulator. Nat Rev Immunol 10, 778–786 (2010).
2. Baumgarth, N. The double life of a B-1 cell: self-reactivity selects for protective effector functions. Nat Rev Immunol 11, 34–46 (2011).
3. Baker, N. & Ehrenstein, M. R. Cutting edge: selection of B lymphocyte subsets is regulated by natural IgM. J Immunol 169, 6686–6690 (2002).
4. Nguyen, T. T., Elsner, R. A. & Baumgarth, N. Natural IgM Prevents Autoimmunity by Enforcing B Cell Central Tolerance Induction. J Immunol (2015).
5. Pillai, S. & Cariappa, A. The follicular versus marginal zone B lymphocyte cell fate decision. Nat Rev Immunol 9, 767–777 (2009).
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