Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution-Reference-Cited by-同舟云学术

Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution

Published:2021-04-16 Issue:1 Volume:11 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Semenov Konstantin N.,Ivanova Daria A.,Ageev Sergei V.,Petrov Andrey V.,Podolsky Nikita E.,Volochaeva Ekaterina M.,Fedorova Ekaterina M.,Meshcheriakov Anatolii A.,Zakharov Egor E.,Murin Igor V.,Sharoyko Vladimir V.

Abstract

AbstractThe article is devoted to the study of the pharmacokinetics of fullerene C60 in oil and micellar forms, analysis of its content in blood, liver, lungs, kidneys, heart, brain, adrenal glands, thymus, testicles, and spleen. The highest accumulation of C60 was found in the liver and adrenal glands. As a result of the studies carried out, it was shown that the bioavailability of C60 in the micellar form is higher than that in an oil solution.

Funder

Russian Foundation for Basic Research

Council on grants of the President of the Russian Federation

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-021-87014-3.pdf

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