Ascorbic acid encapsulated into negatively charged liposomes exhibits increased skin permeation, retention and enhances collagen synthesis by fibroblasts
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-36682-9.pdf
Reference64 articles.
1. Kishimoto, Y. et al. Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts. Biochemical and Biophysical Research Communications 430, 579–584, https://doi.org/10.1016/j.bbrc.2012.11.110 (2013).
2. Phillips, C. L., Combs, S. B. & Pinnell, S. R. Effects of ascorbic acid on proliferation and collagen synthesis in relation to the donor age of human dermal fibroblasts. The Journal of investigative dermatology 103, 228–232 (1994).
3. Nusgens, B. V. et al. Topically applied vitamin C enhances the mRNA level of collagens I and III, their processing enzymes and tissue inhibitor of matrix metalloproteinase 1 in the human dermis. The Journal of investigative dermatology 116, 853–859, https://doi.org/10.1046/j.0022-202x.2001.01362.x (2001).
4. Tajima, S. & Pinnell, S. R. Ascorbic acid preferentially enhances type I and III collagen gene transcription in human skin fibroblasts. Journal of Dermatological Science 11, 250–253, https://doi.org/10.1016/0923-1811(95)00640-0 (1996).
5. Padayatty, S. J. et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. Journal of the American College of Nutrition 22, 18–35 (2003).
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