Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-17201-8.pdf
Reference157 articles.
1. Dierssen, M. Down syndrome: the brain in trisomic mode. Nature reviews. Neuroscience 13, 844–858 (2012).
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3. Vicari, S., Pontillo, M. & Armando, M. Neurodevelopmental and psychiatric issues in Down’s syndrome: assessment and intervention. Psychiatr Genet 23, 95–107 (2013).
4. Edgin, J. O., Mason, G. M., Spanò, G., Fernández, A. & L. N. Human and mouse model cognitive phenotypes in Down syndrome: implications for assessment. Prog Brain Res 197, 123–151 (2012).
5. Reeves, R. H. et al. A mouse model for Down syndrome exhibits learning and behaviour deficits. Nat Genet 11, 177–184 (1995).
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