Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr3-Reference-Cited by-同舟云学术

Runx2 is required for the proliferation of osteoblast progenitors and induces proliferation by regulating Fgfr2 and Fgfr3

Published:2018-09-10 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Kawane Tetsuya,Qin Xin,Jiang Qing,Miyazaki Toshihiro,Komori Hisato,Yoshida Carolina Andrea,Matsuura-Kawata Viviane Keiko dos Santos,Sakane Chiharu,Matsuo Yuki,Nagai Kazuhiro,Maeno Takafumi,Date Yuki,Nishimura Riko,Komori Toshihisa

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-31853-0.pdf

Reference62 articles.

1. Komori, T. Signaling networks in RUNX2-dependent bone development. J Cell Biochem 112, 750–755 (2011).

2. Nakashima, K. & de Crombrugghe, B. Transcriptional mechanisms in osteoblast differentiation and bone formation. Trends in Genetics 19, 458–466 (2003).

3. Galindo, M. et al. The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts. J Biol Chem 280, 20274–20285 (2005).

4. Ghali, O., Chauveau, C., Hardouin, P., Broux, O. & Devedjian, J. C. TNF-α’s effects on proliferation and apoptosis in human mesenchymal stem cells depend on RUNX2 expression. J Bone Miner Res 25, 1616–1626 (2010).

5. Lucero, C. M. et al. The cancer‐related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell lines. J Cell Physiol 228, 714–723 (2013).

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