Author:
Balázs Nóra,Ajtay András,Oberfrank Ferenc,Bereczki Dániel,Kovács Tibor
Abstract
AbstractHungary has a single-payer health insurance system covering 10 million inhabitants. All medical reports of the in- and outpatient specialist services were collected in the NEUROHUN database. We used ICD-10 codes of Alzheimer’s disease (AD), vascular dementia (VaD), miscellaneous dementia group and mild cognitive impairment (MCI) for the inclusion of the patients. Incidence, prevalence and survival of different dementias and MCI were calculated and analyzed depending on the diagnoses given by neurological or psychiatric services or both. Between 2011 and 2016, the mean crude incidence of all dementias was 242/100,000/year, whereas the age standardized incidence was 287/100,000/year. Crude and age standardized mean prevalence rates were 570/100,000 and 649/100,000, respectively. There were significantly more VaD diagnoses than AD, the VaD:AD ratio was 2.54:1, being the highest in patients with psychiatric diagnoses only (4.85:1) and the lowest in patients with only neurological diagnoses (1.32:1). The median survival after the first diagnosis was 3.01 years regarding all dementia cases. Compared to international estimates, the prevalence of dementia and MCI is considerably lower in Hungary and the VaD:AD ratio is reversed.
Funder
Hungarian Brain Research Program NAP2.0
Publisher
Springer Science and Business Media LLC
Reference36 articles.
1. Petersen, R. C. Mild cognitive impairment as a diagnostic entity. J. Intern. Med. 256, 183–194 (2004).
2. Elahi, F. M. & Miller, B. L. A clinicopathological approach to the diagnosis of dementia. Nat. Rev. Neurol. 13, 457–476 (2017).
3. Prince, M., Wimo, A.G.M., Ali, G.C., Wu, Y.T. & Prina, M. World Alzheimer Report 2015: The global impact of dementia: an analysis of prevalence, incidence, cost and trends. (Alzheimer’s Disease International, London). https://www.alzint.org/resource/world-alzheimer-report-2015/. Accessed 4 Jan 2021
4. GBD 2016 Dementia Collaborator. Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990–2016: A systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 18, 88–106 (2019).
5. Prince, M. et al. The global prevalence of dementia: A systematic review and metaanalysis. Alzheimers Dement. 9, 63-75.e2 (2013).
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献