Solid stress-induced migration is mediated by GDF15 through Akt pathway activation in pancreatic cancer cells-Reference-Cited by-同舟云学术

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Solid stress-induced migration is mediated by GDF15 through Akt pathway activation in pancreatic cancer cells

Published:2019-01-30 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Kalli Maria,Minia Angeliki,Pliaka Vaia,Fotis Christos,Alexopoulos Leonidas G.,Stylianopoulos Triantafyllos

Funder

EC | European Research Council

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-37425-6.pdf

Reference44 articles.

1. Kalli, M. & Stylianopoulos, T. Defining the Role of Solid Stress and Matrix Stiffness in Cancer Cell Proliferation and Metastasis. Frontiers in oncology 8, 55 (2018).

2. Jain, R. K., Martin, J. D. & Stylianopoulos, T. The role of mechanical forces in tumor growth and therapy. Annual review of biomedical engineering 16, 321–346 (2014).

3. Stylianopoulos, T., Munn, L. L. & Jain, R. K. Reengineering the Physical Microenvironment of Tumors to Improve Drug Delivery and Efficacy: From Mathematical Modeling to Bench to Bedside. Trends in cancer 4, 292–319 (2018).

4. Helmlinger, G., Netti, P. A., Lichtenbeld, H. C., Melder, R. J. & Jain, R. K. Solid stress inhibits the growth of multicellular tumor spheroids. Nature biotechnology 15, 778–783 (1997).

5. Cheng, G., Tse, J., Jain, R. K. & Munn, L. L. Micro-environmental mechanical stress controls tumor spheroid size and morphology by suppressing proliferation and inducing apoptosis in cancer cells. PloS one 4, e4632 (2009).

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