Optimization of the 5ʹ untranslated region of mRNA vaccines
Author:
Funder
National Science and Technology Major Project
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41598-024-70792-x.pdf
Reference34 articles.
1. Pollard, C., De Koker, S., Saelens, X., Vanham, G. & Grooten, J. Challenges and advances towards the rational design of mRNA vaccines. Trends Mol. Med. 19(12), 705–713. https://doi.org/10.1016/j.molmed.2013.09.002 (2013).
2. Szabó, G. T., Mahiny, A. J. & Vlatkovic, I. COVID-19 mRNA vaccines: Platforms and current developments. Mol. Ther. 30(5), 1850–1868. https://doi.org/10.1016/j.ymthe.2022.02.016 (2022).
3. Baden, L. R. et al. Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine. New Engl. J. Med. 384(5), 403–416. https://doi.org/10.1056/nejmoa2035389 (2021).
4. Polack, F. P. et al. Safety and efficacy of the BNT162b2 mRNA covid-19 vaccine. New Engl. J. Med. 383(27), 2603–2615. https://doi.org/10.1056/nejmoa2034577 (2020).
5. Van Lint, S., Heirman, C., Thielemans, K. & Breckpot, K. mRNA: From a chemical blueprint for protein production to an off-the-shelf therapeutic. Hum. Vaccin. Immunother. 9(2), 265–274. https://doi.org/10.4161/hv.22661 (2013).
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