Author:
Nevue Alexander A.,Lovell Peter V.,Wirthlin Morgan,Mello Claudio V.
Abstract
Abstract
How the evolution of complex behavioral traits is associated with the emergence of novel brain pathways is largely unknown. Songbirds, like humans, learn vocalizations via tutor imitation and possess a specialized brain circuitry to support this behavior. In a comprehensive in situ hybridization effort, we show that the zebra finch vocal robust nucleus of the arcopallium (RA) shares numerous markers (e.g. SNCA, PVALB) with the adjacent dorsal intermediate arcopallium (AId), an avian analog of mammalian deep cortical layers with involvement in motor function. We also identify markers truly unique to RA and thus likely linked to modulation of vocal motor function (e.g. KCNC1, GABRE), including a subset of the known shared markers between RA and human laryngeal motor cortex (e.g. SLIT1, RTN4R, LINGO1, PLXNC1). The data provide novel insights into molecular features unique to vocal learning circuits, and lend support for the motor theory for vocal learning origin.
Funder
National Institutes of Health
National Science Foundation
Publisher
Springer Science and Business Media LLC
Reference107 articles.
1. Zeigler, H. P. & Marler, P. In Behavioral Neurobiology of Birdsong (eds Zeigler, H. P. & Marler, P.) (New York Academy of Sciences, New York, 2004).
2. Reiner, A. et al. Revised nomenclature for avian telencephalon and some related brainstem nuclei. J. Comp. Neurol. 473(3), 377–414 (2004).
3. Jarvis, E. D. et al. Avian brains and a new understanding of vertebrate brain evolution. Nat. Rev. Neurosci. 6(2), 151–159 (2005).
4. Lovell, P. V. et al. ZEBrA: Zebra finch expression brain atlas—A resource for comparative molecular neuroanatomy and brain evolution studies. J. Comp. Neurol. 528, 2099–2131 (2020).
5. Nottebohm, F., Stokes, T. M. & Leonard, C. M. Central control of song in the canary, Seinus canarius. J. Comp. Neurol. 165(4), 457–486 (1976).
Cited by
20 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献