Cathelicidin-trypsin inhibitor loop conjugate represents a promising antibiotic candidate with protease stability
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-02050-2.pdf
Reference64 articles.
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3. Hancock, R. E. & Sahl, H.-G. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat. Biotechnol. 24, 1551–1557, doi: 10.1038/nbt1267 (2006).
4. Giacometti, A. et al. In vitro effect on Cryptosporidium parvum of short-term exposure to cathelicidin peptides. J. Antimicrob. Chemother. 51, 843–847, doi: 10.1093/jac/dkg149 (2003).
5. Rapala-Kozik, M. et al. Inactivation of the antifungal and immunomodulatory properties of human cathelicidin LL-37 by aspartic proteases produced by the pathogenic yeast Candida albicans. Infect. Immun. 83, 2518–2530, doi: 10.1128/IAI.00023-15 (2015).
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