Uric acid enhances alteplase-mediated thrombolysis as an antioxidant
Author:
Funder
This study was supported by grants from the Mihara Cerebrovascular Disorder Research Promotion Fund (to I.M.).
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-34220-1.pdf
Reference32 articles.
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4. Gravanis, I. & Tsirka, S. E. Tissue-type plasminogen activator as a therapeutic target in stroke. Expert Opin. Ther. Targets 12, 159–170 (2008).
5. Amaro, S. et al. Uric acid therapy prevents early ischemic stroke progression: a tertiary analysis of the URICO-ICTUS trial (efficacy study of combined treatment with uric acid and rtPA in acute ischemic stroke). Stroke 47, 2874–2876 (2016).
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