Development of a rapid and economic in vivo electrocardiogram platform for cardiovascular drug assay and electrophysiology research in adult zebrafish
Author:
Funder
Ministry of Science and Technology, Taiwan
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-33577-7.pdf
Reference34 articles.
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2. Vornanen, M. & Hassinen, M. Zebrafish heart as a model for human cardiac electrophysiology. Channels (Austin) 10, 101–110, https://doi.org/10.1080/19336950.2015.1121335 (2016).
3. Milan, D. J., Jones, I. L., Ellinor, P. T. & MacRae, C. A. In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation. American journal of physiology. Heart and circulatory physiology 291, H269–273, https://doi.org/10.1152/ajpheart.00960.2005 (2006).
4. Leong, I. U., Skinner, J. R., Shelling, A. N. & Love, D. R. Zebrafish as a model for long QT syndrome: the evidence and the means of manipulating zebrafish gene expression. Acta Physiol (Oxf) 199, 257–276, https://doi.org/10.1111/j.1748-1716.2010.02111.x (2010).
5. Liu, C. C., Li, L., Lam, Y. W., Siu, C. W. & Cheng, S. H. Improvement of surface ECG recording in adult zebrafish reveals that the value of this model exceeds our expectation. Scientific reports 6, 25073, https://doi.org/10.1038/srep25073 (2016).
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