Abstract
AbstractAlthough Argentina and Chile are neighboring countries, gastric cancer (GC) is the first cancer death cause in the Chilean male population, while it is ranked in fifth place for Argentinean males. This study is the first to identify the differential time-patterns associated with the age-period-cohort effects for the last few decades (1990–2015) in these Southern Cone countries. Trends of age-standardized truncated mortality rates (ASMR) for GC were analyzed using log-linear Poisson age-period-cohort models, including cubic splines for each component. The ASMR trends for GC decreased in both sexes but more considerably in Chile and more favorably for males (annual percentage changes 2002–2015 = −3.5, 95%CI: −3.9 to −3.1). Moreover, GC age-specific mortality rates were noticeably higher in Chile. A favorable decreasing mortality risk throughout the periods (from 2000) and by cohort was observed for both countries; however, the risk reduction has stabilized in younger female cohorts since 1950-cohort. In conclusion, overall favorable decreasing trends for GC mortality were found; however, when age-period-cohort effects were disentangled, Chile and younger female cohorts showed a more unfavorable scenario. Obesity, lifestyles, and environmental conditions (like altitude) may explain country differences. This analytical approach may be a valuable tool to be replicated in other countries with no population-based cancer registries and acceptable mortality data quality.
Publisher
Springer Science and Business Media LLC
Reference32 articles.
1. Bray, F. et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Cancer J. Clin. 68, 394–424, https://doi.org/10.3322/caac.21492 (2018).
2. Sierra, M. S., Cueva, P., Bravo, L. E. & Forman, D. Stomach cancer burden in Central and South America. Cancer Epidemiol. 44, S62–S73, https://doi.org/10.1016/j.canep.2016.03.008 (2016).
3. Ferro, A. et al. Worldwide trends in gastric cancer mortality (1980–2011), with predictions to 2015, and incidence by subtype. Eur. J. Cancer. 50, 1330–1344, https://doi.org/10.1016/j.ejca.2014.01.029 (2014).
4. Pou, S. A., Díaz, M., del., P. & Osella, A. R. Applying multilevel model to the relationship of dietary patterns and colorectal cancer: an ongoing case-control study in Córdoba, Argentina. Eur. J. Nutr. 51, 755–64, https://doi.org/10.1007/s00394-011-0255-7 (2012).
5. Ferlay, J. et al. Global Cancer Observatory: Cancer Today. 2018. Lyon, France: International Agency for Research on Cancer, https://gco.iarc.fr/today (accessed 2019).
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献