CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-00098-8.pdf
Reference48 articles.
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2. Li, J. et al. Submembrane ATP and Ca2+ kinetics in alpha-cells: unexpected signaling for glucagon secretion. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 29, 3379–3388, doi: 10.1096/fj.14-265918 (2015).
3. Zhang, Q. et al. Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes. Cell Metab 18, 871–882, doi: 10.1016/j.cmet.2013.10.014 (2013).
4. MacDonald, P. E. et al. A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans. PLoS biology 5, e143 (2007).
5. Ramracheya, R. et al. Membrane potential-dependent inactivation of voltage-gated ion channels in alpha-cells inhibits glucagon secretion from human islets. Diabetes 59, 2198–2208, doi: 10.2337/db09-1505 (2010).
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