Acute and chronic hypoxia differentially predispose lungs for metastases
Author:
Funder
Cancer Research UK
Wellcome Trust
Breast Cancer Now
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-46763-y.pdf
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3. Gupta, G. P. et al. Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature 446, 765–770, https://doi.org/10.1038/nature05760 (2007).
4. Gong, H. et al. HIF2alpha signaling inhibits adherens junctional disruption in acute lung injury. The Journal of clinical investigation 125, 652–664, https://doi.org/10.1172/jci77701 (2015).
5. Le Bras, A. et al. HIF-2alpha specifically activates the VE-cadherin promoter independently of hypoxia and in synergy with Ets-1 through two essential ETS-binding sites. Oncogene 26, 7480–7489, https://doi.org/10.1038/sj.onc.1210566 (2007).
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