Discovery of novel oestrogen receptor α agonists and antagonists by screening a revisited privileged structure moiety for nuclear receptors-Reference-Cited by-同舟云学术

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Discovery of novel oestrogen receptor α agonists and antagonists by screening a revisited privileged structure moiety for nuclear receptors

Published:2019-07-09 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Masuya Takahiro,Iwamoto Masaki,Liu Xiaohui,Matsushima Ayami

Funder

MEXT | Japan Society for the Promotion of Science

The Toyota Physical and Chemical Research Institute, The Kato Memorial Bioscience Foundation

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-46272-y.pdf

Reference51 articles.

1. Matsushima, A., Liu, X., Okada, H., Shimohigashi, M. & Shimohigashi, Y. Bisphenol AF is a full agonist for the estrogen receptor ERα but a highly specific antagonist for ERβ. Environ. Health Perspect. 118, 1267–1272 (2010).

2. vom Saal, F. S. & Hughes, C. An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. Environ. Health Perspect. 113, 926–933 (2005).

3. Nagel, S. C. et al. Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol. Environ. Health Perspect. 105, 70–76 (1997).

4. Gupta, C. Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals. Proc. Soc. Exp. Biol. Med. 224, 61–68 (2000).

5. vom Saal, F. S. et al. A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior. Toxicol. Ind. Health 14, 239–260 (1998).

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