Clinical dosage of meclozine promotes longitudinal bone growth, bone volume, and trabecular bone quality in transgenic mice with achondroplasia
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-07044-8.pdf
Reference23 articles.
1. Horton, W. A., Hall, J. G. & Hecht, J. T. Achondroplasia. Lancet 370, 162–172 (2007).
2. Rousseau, F. et al. Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia. Nature 371, 252–254 (1994).
3. Shiang, R. et al. Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia. Cell 78, 335–342 (1994).
4. Pauli, R. M. et al. Apnea and sudden unexpected death in infants with achondroplasia. J Pediatr 104, 342–348 (1984).
5. Matsushita, M. et al. Low bone mineral density in achondroplasia and hypochondroplasia. Pediatr Int 58, 705–708 (2016).
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