Investigating the neuroprotective effect of AAV-mediated β-synuclein overexpression in a transgenic model of synucleinopathy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-35825-2.pdf
Reference36 articles.
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2. Mougenot, A. L. et al. Prion-like acceleration of a synucleinopathy in a transgenic mouse model. Neurobiology of aging 33, 2225–2228, https://doi.org/10.1016/j.neurobiolaging.2011.06.022 (2012).
3. Betemps, D. et al. Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological alpha-synuclein by enhanced ELISA. Acta Neuropathologica Communications 2, 29, https://doi.org/10.1186/2051-5960-2-29 (2014).
4. Betemps, D. et al. Detection of Disease-associated alpha-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated alpha-synuclein. Journal of visualized experiments: JoVE, e52752, https://doi.org/10.3791/52752 (2015).
5. Sargent, D. et al. ‘Prion-like’ propagation of the synucleinopathy of M83 transgenic mice depends on the mouse genotype and type of inoculum. Journal of neurochemistry 143, 126–135, https://doi.org/10.1111/jnc.14139 (2017).
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