Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-03397-2.pdf
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4. Swaroop, A., Chew, E. Y., Rickman, C. B. & Abecasis, G. R. Unraveling a multifactorial late-onset disease: from genetic susceptibility to disease mechanisms for age-related macular degeneration. Annual review of genomics and human genetics 10, 19–43, doi: 10.1146/annurev.genom.9.081307.164350 (2009).
5. Gehrs, K. M., Anderson, D. H., Johnson, L. V. & Hageman, G. S. Age-related macular degeneration–emerging pathogenetic and therapeutic concepts. Annals of medicine 38, 450–471, doi: 10.1080/07853890600946724 (2006).
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