The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue-Reference-Cited by-同舟云学术

The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue

Published:2018-10-05 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Komakula Sai Santosh Babu,Tumova Jana,Kumaraswamy Deeptha,Burchat Natalie,Vartanian Vladimir,Ye Hong,Dobrzyn Agnieszka,Lloyd R. Stephen,Sampath Harini

Funder

EC | Horizon 2020

U.S. Department of Health & Human Services | National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-33151-1.pdf

Reference69 articles.

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2. Audebert, M. et al. Alterations of the DNA repair gene OGG1 in human clear cell carcinomas of the kidney. Cancer research 60, 4740–4744 (2000).

3. K, C. S., Carcamo, J. M. & Golde, D. W. Antioxidants prevent oxidative DNA damage and cellular transformation elicited by the over-expression of c-MYC. Mutation research 593, 64–79, https://doi.org/10.1016/j.mrfmmm.2005.06.015 (2006).

4. Abolhassani, N. et al. Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer’s disease brain. Mechanisms of ageing and development 161, 95–104, https://doi.org/10.1016/j.mad.2016.05.005 (2017).

5. Sampath, H., McCullough, A. K. & Lloyd, R. S. Regulation of DNA glycosylases and their role in limiting disease. Free Radic Res 46, 460–478 (2012).

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