Targeting Ligand Specificity Linked to Tumor Tissue Topological Heterogeneity via Single-Cell Micro-Pharmacological Modeling-Reference-Cited by-同舟云学术

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Targeting Ligand Specificity Linked to Tumor Tissue Topological Heterogeneity via Single-Cell Micro-Pharmacological Modeling

Published:2018-02-26 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Karolak Aleksandra,Estrella Veronica C.,Huynh Amanda S.,Chen Tingan,Vagner Josef,Morse David L.,Rejniak Katarzyna A.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-21883-z.pdf

Reference46 articles.

1. Abramson, R. Overview of targeted therapies for cancer. My Cancer Genome (2016).

2. Huang, M., Shen, A., Ding, J. & Geng, M. Molecularly targeted cancer therapy: some lessons from the past decade. Trends in pharmacological sciences 35, 41–50, https://doi.org/10.1016/j.tips.2013.11.004 (2014).

3. Fisher, R., Pusztai, L. & Swanton, C. Cancer heterogeneity: implications for targeted therapeutics. British journal of cancer 108, 479–485, https://doi.org/10.1038/bjc.2012.581 (2013).

4. Au, J. L., Yeung, B. Z., Wientjes, M. G., Lu, Z. & Wientjes, M. G. Delivery of cancer therapeutics to extracellular and intracellular targets: Determinants, barriers, challenges and opportunities. Adv Drug Deliv Rev 97, 280–301, https://doi.org/10.1016/j.addr.2015.12.002 (2016).

5. Greaves, M. & Maley, C. C. Clonal evolution in cancer. Nature 481, 306–313, https://doi.org/10.1038/nature10762 (2012).

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