Investigating screw-agitator speed ratio impact on feeding performance in pharmaceutical manufacturing using discrete element method
Author:
Funder
Bijzonder Onderzoeksfonds UGent
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41598-024-72288-0.pdf
Reference30 articles.
1. Nagy, Z. K., El Hagrasy, A. & Litster, J. Continuous Pharmaceutical Processing Vol. 42 (Springer, 2020).
2. De Souter, L. et al. Elucidation of the powder flow pattern in a twin-screw LIW-feeder for various refill regimes. Int. J. Pharm. 631, 122534 (2023).
3. Waeytens, R. et al. An extended 3-compartment model for describing step change experiments in pharmaceutical twin-screw feeders at different refill regimes. Int. J. Pharm. 627, 122154 (2022).
4. Grieves, M. & Vickers, J. Digital twin: Mitigating unpredictable, undesirable emergent behavior in complex systems. Transdisciplinary perspectives on complex systems: New findings and approaches 85–113 (2017).
5. Bekaert, B. et al. Determination of a quantitative relationship between material properties, process settings and screw feeding behavior via multivariate data-analysis. Int. J. Pharm. 602, 120603 (2021).
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