Abstract
AbstractSingle fibre electromyography is the most sensitive neurophysiological test for the diagnosis of neuromuscular junction disorders, particularly myasthenia gravis. The study aimed at establishing concentric needle (CN) normal jitter values for voluntarily activated orbicularis-oculi (V-OOc) & Frontalis (V-FRO) muscles in Sudanese population. 57 healthy volunteers (20 males & 37 females) were included in the study (mean Age 43.6 ± 14.2 years, range 18–70 years). V-OOc and V-FRO were tested in the same individual using CN. Jitter values were expressed as the mean consecutive difference (MCD) of 30 potential pairs in microseconds. The mean jitter, mean individual fibre pairs jitter & mean outliers jitter values with (upper 95% Confidence Limit-CL) for [OOc] were [26.9 ± 3.3 (31.97), 26.1 ± 8.9 (41.8) & 38.5 ± 5.7 (49.0) µs] & for [FRO] were [27.1 ± 3.0 (31.32), 26.4 ± 9.4 (42.9) & 39.9 ± 5 (49.2) µs] respectively. The suggested practical upper limits for mean jitter & for outliers were (32, 49 µs) for OOc & (31, 49 µs) for FRO. Our CN-jitter values were within the range of the few published studies. The study was unique in that it established and compared between CN reference jitter values of two voluntarily activated facial muscles (V-OOc & V-FRO) in the same individual in large number of healthy subjects.
Publisher
Springer Science and Business Media LLC
Reference44 articles.
1. Ekstedt, J. & Stalberg, E. A method of recording extracellular action potentials of single muscle fibres and measuring their conduction velocity in voluntary activated human muscle. Bull. Amer. Assoc. Electromyogr. Electrodiagn. 10, 16 (1963).
2. Ekstedt, J. Human Single Muscle Fiber Action Potentials. Extracellular Recording During Voluntary and Chemical Activation. With Some Comments on End-Plate Physiology and on the Fiber Arrangement of the Motor Unit. Acta Physiol Scand Suppl. suppl 226(1+) (1964).
3. Ekstedt, J., Haggqvist, P. & Stalberg, E. The construction of needle multi-electrodes for single fiber electromyography. Electroencephalogr Clin Neurophysiol. 27, 540–3 (1969).
4. Sanders, D. B., Howard, J. & James, F. AAEE Minimonograph# 25: Single fiber electromyography in myasthenia gravis. Muscle & Nerve. 9, 809–819 (1986).
5. Sanders, D. B. Clinical impact of single-fiber electromyography. Muscle Nerve. Suppl 11, S15–20 (2002).
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