Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-00791-8.pdf
Reference32 articles.
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3. Imamovic, L. & Sommer, M. O. Use of collateral sensitivity networks to design drug cycling protocols that avoid resistance development. Science Translational Medicine 5, 204ra132–204ra132, doi: 10.1126/scitranslmed.3006609 (2013).
4. Shaw, A. T. et al. Resensitization to crizotinib by the lorlatinib ALK resistance mutation l1198f. New England Journal of Medicine 374, 54–61, doi: 10.1056/NEJMoa1508887 (2016).
5. Zhao, B. et al. Exploiting temporal collateral sensitivity in tumor clonal evolution. Cell 165, 234–246, doi: 10.1016/j.cell.2016.01.045 (2016).
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