CSA13 inhibits colitis-associated intestinal fibrosis via a formyl peptide receptor like-1 mediated HMG-CoA reductase pathway
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-16753-z.pdf
Reference34 articles.
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2. Katsanos, K. H. et al. Fast-track drug approval in inflammatory bowel diseases. Ann Gastroenterol 29, 439–444 (2016).
3. Bucki, R. et al. Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection. Antimicrob Agents Chemother 59, 6274–6282, https://doi.org/10.1128/AAC.00653-15 (2015).
4. De, Y. et al. LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells. J Exp Med 192, 1069–1074 (2000).
5. Lai, X. Z. et al. Ceragenins: cholic acid-based mimics of antimicrobial peptides. Acc Chem Res 41, 1233–1240, https://doi.org/10.1021/ar700270t (2008).
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