Increased sporulation underpins adaptation of Clostridium difficile strain 630 to a biologically–relevant faecal environment, with implications for pathogenicity-Reference-Cited by-同舟云学术

Increased sporulation underpins adaptation of Clostridium difficile strain 630 to a biologically–relevant faecal environment, with implications for pathogenicity

Published:2018-11-12 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Ternan Nigel George^ORCID,Moore Nicola Diana,Smyth Deborah,McDougall Gordon James^ORCID,Allwood James William^ORCID,Verrall Susan,Gill Christopher Ian Richard^ORCID,Dooley James Stephen Gerard^ORCID,McMullan Geoff^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-35050-x.pdf

Reference97 articles.

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3. Jarrad, A. M., Karoli, T., Blaskovich, M. A., Lyras, D. & Cooper, M. A. Clostridium difficile drug pipeline: challenges in discovery and development of new agents. J. Med. Chem. 58, 5164–5185 (2015).

4. Kuehne, S. A. et al. The role of toxin A and toxin B in Clostridium difficile infection. Nature. 467, 711–713 (2010).

5. Carter, G. P., Rood, J. I. & Lyras, D. The role of toxin A and toxin B in the virulence of Clostridium difficile. Trends Microbiol. 20, 21–29 (2012).

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