Tsc1 ablation in Prx1 and Osterix lineages causes renal cystogenesis in mouse
Author:
Funder
National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-018-37139-9.pdf
Reference44 articles.
1. Bonnet, C. S. et al. Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis. Hum Mol Genet 18, 2166–2176 (2009).
2. Kwiatkowski, D. J. et al. A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Hum Mol Genet 11, 525–534 (2002).
3. Zhou, J., Brugarolas, J. & Parada, L. F. Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1. Hum Mol Genet 18, 4428–4441 (2009).
4. von Ranke, F. M. et al. Imaging of tuberous sclerosis complex: a pictorial review. Radiol Bras 50, 48–54 (2017).
5. Kato, I. et al. Epithelioid angiomyolipoma of the kidney. Pathol Int 59, 38–43 (2009).
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