Development of Customized [18F]Fluoride Elution Techniques for the Enhancement of Copper-Mediated Late-Stage Radiofluorination
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-00110-1.pdf
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3. Stewart, M. N., Hockley, B. G. & Scott, P. J. H. Green Approaches to Late-stage Fluorination: Radiosyntheses of 18F-Labelled Radiopharmaceuticals in Ethanol and Water. Chem. Commun. 51, 14805–14808 (2015).
4. Kim, D. W. et al. Facile Nucleophilic Fluorination Reactions using tert-Alcohols as a Reaction Medium: Significantly Enhanced Reactivity of Alkali Metal Fluorides and Improved Selectivity. J. Org. Chem. 73, 957–962 (2008).
5. Sergeev, M. E., Morgia, F., Lazari, M., Wang, C. & van Dam, R. M. Titania-catalyzed Radiofluorination of Tosylated Precursors in Highly Aqueous Medium. J. Am. Chem. Soc. 137, 5686–5694 (2015).
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