Targeting SxIP-EB1 interaction: An integrated approach to the discovery of small molecule modulators of dynamic binding sites
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-15502-6.pdf
Reference39 articles.
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3. Maurer, S. P., Fourniol, F. J., Bohner, G., Moores, C. A. & Surrey, T. EBs recognize a nucleotide-dependent structural cap at growing microtubule ends. Cell 149, 371–382 (2012).
4. Kumar, P. et al. Multisite phosphorylation disrupts arginine-glutamate salt bridge networks required for binding of cytoplasmic linker-associated protein 2 (CLASP2) to end-binding protein 1 (EB11). J. Biol. Chem. 287, 17050–17064 (2012).
5. Honnappa, S. et al. An EB1-binding motif acts as a microtubule tip localization signal. Cell 138, 366–376 (2009).
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