CarcinoPred-EL: Novel models for predicting the carcinogenicity of chemicals using molecular fingerprints and ensemble learning methods
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-02365-0.pdf
Reference63 articles.
1. Parasuraman, S. Toxicological screening. J. Pharmacol. Pharmacother. 2, 74–79, doi: 10.4103/0976-500X.81895 (2011).
2. Segall, M. D. & Barber, C. Addressing toxicity risk when designing and selecting compounds in early drug discovery. Drug Discov. Today. 19, 688–693, doi: 10.1016/j.drudis.2014.01.006 (2014).
3. Onakpoya, I. J., Heneghan, C. J. & Aronson, J. K. Post-marketing withdrawal of 462 medicinal products because of adverse drug reactions: a systematic review of the world literature. BMC Med. 14, 10, doi: 10.1186/s12916-016-0553-2 (2016).
4. Jacobs, A. & Hatfield, K. History of chronic toxicity and animal carcinogenicity studies for pharmaceuticals. Vet. Pathol. 50, 324–333, doi: 10.1177/0300985812450727 (2013).
5. Jacobs, A. C. & Brown, P. C. Regulatory Forum Opinion Piece* Transgenic/Alternative Carcinogenicity Assays: A Retrospective Review of Studies Submitted to CDER/FDA 1997–2014. Toxicol. Pathol. 43, 605–610, doi: 10.1177/0192623314566241 (2015).
Cited by 171 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Unlocking the potential of AI: Machine learning and deep learning models for predicting carcinogenicity of chemicals;Journal of Environmental Science and Health, Part C;2024-09-03
2. Enriching Anticancer Drug Pipeline with Potential Inhibitors of Cyclin-Dependent Kinase-8 Identified from Natural Products;OMICS: A Journal of Integrative Biology;2024-09-01
3. Structure-based drug-development study against fibroblast growth factor receptor 2: molecular docking and Molecular dynamics simulation approaches;Scientific Reports;2024-08-21
4. Accurate Prediction of Rat Acute Oral Toxicity and Reference Dose for Thousands of Polycyclic Aromatic Hydrocarbon Derivatives Based on Chemometric QSAR and Machine Learning;Environmental Science & Technology;2024-08-13
5. Repurposing of Drug Bank Compounds against Plasmodium falciparum Dihydroorotate Dehydrogenase as novel anti malarial drug candidates by Computational approaches;In Silico Pharmacology;2024-07-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3