Engineered Carbonic Anhydrase VI-Mimic Enzyme Switched the Structure and Affinities of Inhibitors
Author:
Funder
EC | Horizon 2020 Framework Programme
Lietuvos Mokslo Taryba
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-49094-0.pdf
Reference86 articles.
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2. Frost, S. C. Physiological functions of the alpha class of carbonic anhydrases. Subcell. Biochem. 75, 9–30 (2014).
3. Aggarwal, M., Boone, C. D., Kondeti, B. & McKenna, R. Structural annotation of human carbonic anhydrases. J Enzyme Inhib Med Chem 28, 267–277 (2013).
4. Mincione, F. et al. Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma. Bioorg. Med. Chem. Lett. 15, 3821–3827 (2005).
5. Thiry, A., Dogné, J.-M., Supuran, C. T. & Masereel, B. Carbonic anhydrase inhibitors as anticonvulsant agents. Curr Top Med Chem 7, 855–864 (2007).
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