High-throughput sequencing of IgG B-cell receptors reveals frequent usage of the rearranged IGHV4–28/IGHJ4 gene in primary immune thrombocytopenia
Author:
Funder
MEXT | Japan Society for the Promotion of Science
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-45264-2.pdf
Reference38 articles.
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2. Cines, D. B. & Blanchette, V. S. Immune thrombocytopenic purpura. The New England journal of medicine 346, 995–1008, https://doi.org/10.1056/NEJMra010501 (2002).
3. George, J. N. et al. Idiopathic thrombocytopenic purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood 88, 3–40 (1996).
4. Brezinschek, H. P. et al. Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(−)/IgM+ B cells. The Journal of clinical investigation 99, 2488–2501, https://doi.org/10.1172/jci119433 (1997).
5. Neunert, C. et al. The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia. Blood 117, 4190–4207, https://doi.org/10.1182/blood-2010-08-302984 (2011).
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