Rho-kinase inhibitor Y-27632 and hypoxia synergistically enhance chondrocytic phenotype and modify S100 protein profiles in human chondrosarcoma cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-03958-5.pdf
Reference65 articles.
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3. Woods, A. & Beier, F. RhoA/ROCK signaling regulates chondrogenesis in a context-dependent manner. J Biol Chem 28, 13134–13140 (2006).
4. Matsumoto, E., Furumatsu, T., Kanazawa, T., Tamura, M. & Ozaki, T. ROCK inhibitor prevents the dedifferentiation of human articular chondrocytes. Biochem Biophys Res Commun 420, 124–29 (2012).
5. Furumatsu, T., Matsumoto-Ogawa, E., Tanaka, T., Lu, Z. & Ozaki, T. ROCK inhibition enhances aggrecan deposition and suppresses matrix metalloproteinase-3 production in human articular chondrocytes. Connect Tissue Res 55, 89–95 (2014).
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