Author:
Dean Owen,Anjum Seher,Scott Terri,Ham Lillian,Traino Katherine,Wang Jing,Hunsberger Sally,Powers John H.,Marr Kieren A.,Snow Joseph,Williamson Peter R.
Abstract
AbstractThe morbidity and mortality of cryptococcal meningoencephalitis (CM) in previously healthy, HIV-negative individuals is increasingly recognized. We administered a healthcare associated quality of life (QOL) survey to the largest longitudinally followed cohort of these patients in the United States. We identified moderate or severe self-reported impairment in at least one QOL domain in 61% of subjects at least one year following diagnosis. Self-reported cognitive impairment was noted in 52% and sleep disturbance was noted in 55%. This is the first comprehensive study of cross-sectional long-term QOL in previously healthy patients following cryptococcal infection.
Funder
NIH Medical Research Scholars Program
Division of Intramural Research, National Institute of Allergy and Infectious Diseases
Intramural Research Program, National Institutes of Health, Bethesda, MD
National Cancer Institute
NIAID
Publisher
Springer Science and Business Media LLC
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献