Diversity Modification and Structure-Activity Relationships of Two Natural Products 1β-hydroxy Alantolactone and Ivangustin as Potent Cytotoxic Agents-Reference-Cited by-同舟云学术

Diversity Modification and Structure-Activity Relationships of Two Natural Products 1β-hydroxy Alantolactone and Ivangustin as Potent Cytotoxic Agents

Published:2018-01-29 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Tang Jiang-Jiang,He Qiu-Rui,Dong Shuai,Guo Xin,Wang Yu-Gong,Lei Bei-Lei,Tian Jun-Mian,Gao Jin-Ming

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-20192-9.pdf

Reference56 articles.

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2. Newman, D. J. & Cragg, G. M. Natural products as sources of new drugs from 1981 to 2014. J. Nat. Prod. 79, 629–661 (2016).

3. Wang, G. W. et al. Inula sesquiterpenoids: structural diversity, cytotoxicity and anti-tumor activity. Expert Opin. Inv. Drug 23, 317–345 (2014).

4. Amorim, M. H., Gil da Costa, R. M., Lopes, C. & Bastos, M. M. Sesquiterpene lactones: adverse health effects and toxicity mechanisms. Crit. Rev. Toxicol. 43, 559–579 (2013).

5. Ghantous, A., Gali-Muhtasib, H., Vuorela, H., Saliba, N. A. & Darwiche, N. What made sesquiterpene lactones reach cancer clinical trials? Drug Discov. Today 15, 668–678 (2010).

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