Impact of physiologically shaped pancreatic stent for chronic pancreatitis

Author:

Hori Yasuki,Ichino Yuka,Naitoh Itaru,Hayashi Kazuki,Yoshida Michihiro,Natsume Makoto,Jinno Naruomi,Kato Akihisa,Kachi Kenta,Asano Go,Atsuta Naoki,Sahashi Hidenori,Kataoka Hiromi,Ohara Hirotaka

Abstract

AbstractEndoscopic pancreatic stenting is used to prevent main pancreatic duct obstruction and relieve painful symptoms of chronic pancreatitis. However, the stent typically needs to be exchanged and the rate of adverse events is high. Few studies have evaluated the effect of stent shape on those outcomes. We evaluated the adverse events, stent patency, and total medical cost within 90 days of patients who received an 8.5 French (Fr) physiologically shaped pancreatic stent by comparing these features with those associated with a conventional straight-type stent for ≥ 90 days. The total stent-related adverse event rate was significantly lower for the physiologically shaped pancreatic stent (physiologically shaped, 6.7% [2/30]; straight-type, 50.6% [44/87]; P < 0.001). Stent occlusion was significantly less frequent (P < 0.001) and the total medical costs were significantly lower (P = 0.002) for the physiologically shaped stent. The stent-related adverse event rate was significantly higher for the 10 Fr straight type stent than for the 8.5 Fr physiologically shaped stent (10 Fr, straight-type vs. 8.5 Fr, physiologically shaped: 36.1% [13/36] vs. 6.7% [2/30]; P = 0.007). In conclusion, a physiologically shaped pancreatic stent was superior to a straight-type stent in terms of the patency rate and medical costs.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

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