Bivalent DNA vaccine induces significant immune responses against infectious hematopoietic necrosis virus and infectious pancreatic necrosis virus in rainbow trout
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-06143-w.pdf
Reference61 articles.
1. Abbadi, M. et al. Molecular Evolution and Phylogeography of Co-circulating IHNV and VHSV in Italy. Frontiers in microbiology 7, 1306, doi: 10.3389/fmicb.2016.01306 (2016).
2. LaPatra, S. E. et al. Protection of rainbow trout against infectious hematopoietic necrosis virus four days after specific or semi-specific DNA vaccination. Vaccine 19, 4011–4019 (2001).
3. Tarrab, E. et al. Evidence of a major neutralizable conformational epitope region on VP2 of infectious pancreatic necrosis virus. The Journal of general virology 76(Pt 3), 551–558, doi: 10.1099/0022-1317-76-3-551 (1995).
4. Ye, C. et al. Inhibition of antiviral innate immunity by birnavirus VP3 protein via blockage of viral double-stranded RNA binding to the host cytoplasmic RNA detector MDA5. Journal of virology 88, 11154–11165, doi: 10.1128/JVI.01115-14 (2014).
5. Dadar, M. et al. Protective and immunogenic effects of Escherichia coli-expressed infectious pancreatic necrosis virus (IPNV) VP2-VP3 fusion protein in rainbow trout. Fish & shellfish immunology 47, 390–396, doi: 10.1016/j.fsi.2015.09.007 (2015).
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