Single-cell assessment of transcriptome alterations induced by Scriptaid in early differentiated human haematopoietic progenitors during ex vivo expansion
Author:
Funder
Innovate UK
RCUK | Medical Research Council
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-41803-z.pdf
Reference46 articles.
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2. Engert, A. et al. The european hematology association roadmap for european hematology research: A consensus document. Haematologica 101, 115–208 (2016).
3. Mettananda, S. et al. Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-Thalassemia. Nature Comm. 8, 424–429 (2017).
4. Morgan, R. A., Gray, D., Lomova, A. & Kohn, D. B. Hematopoietic stem cell gene therapy: progress and lessons learned. Cell Stem Cell. 21, 574–590 (2017).
5. Schiroli, G. et al. Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1. Science Trans.l Med. 9, eaan0820 (2017).
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