Author:
Abdollahi-Basir Mohammad Hossein,Mirhosseini-Eshkevari Boshra,Zamani Farzad,Ghasemzadeh Mohammad Ali
Abstract
AbstractA one-pot three component reaction of benzaldehydes, 1H-tetrazole-5-amine, and 3-cyanoacetyl indole in the presence of a new hexamethylenetetramine-based ionic liquid/MIL-101(Cr) metal–organic framework as a recyclable catalyst was explored. This novel catalyst, which was fully characterized by XRD, FE-SEM, EDX, FT-IR, TGA, BET, and TEM exhibited outstanding catalytic activity for the preparation of a range of pharmaceutically important tetrazolo[1,5-a]pyrimidine-6-carbonitriles with good to excellent yields in short reaction time.
Funder
Qom Islamic Azad University
Publisher
Springer Science and Business Media LLC
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