Influence of mismatched and bulged nucleotides on SNP-preferential RNase H cleavage of RNA-antisense gapmer heteroduplexes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-12844-z.pdf
Reference79 articles.
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3. Rodriguez-Lebron, E. & Paulson, H. L. Allele-specific RNA interference for neurological disease. Gene Ther 13, 576–581 (2006).
4. Hu, J. et al. Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs. Nat Biotechnol 27, 478–484 (2009).
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