Astragaloside IV alleviates heart failure via activating PPARα to switch glycolysis to fatty acid β-oxidation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-02360-5.pdf
Reference49 articles.
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4. Kantor, P. F., Lucien, A., Kozak, R. & Lopaschuk, G. D. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. Circulation research 86, 580–588 (2000).
5. Stanley, W. C., Recchia, F. A. & Lopaschuk, G. D. Myocardial substrate metabolism in the normal and failing heart. Physiological reviews 85, 1093–1129, doi: 10.1152/physrev.00006.2004 (2005).
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