Author:
Deschasaux-Tanguy Mélanie,Szabo de Edelenyi Fabien,Druesne-Pecollo Nathalie,Esseddik Younes,Allègre Julien,Srour Bernard,Galan Pilar,Hercberg Serge,Severi Gianluca,Zins Marie,Wiernik Emmanuel,Carrat Fabrice,Ancel Pierre-Yves,Bajos Nathalie,Charles Marie-Aline,Severi Gianluca,Touvier Mathilde,Zins Marie,Kab Sofiane,Renuy Adeline,Le Got Stéphane,Ribet Céline,Pellicer Mireille,Wiernik Emmanuel,Goldberg Marcel,Zins Marie,Artaud Fanny,Gerbouin-Rérolle Pascale,Enguix Mélody,Laplanche Camille,Gomes-Rimav Roselyn,Hoang Lyan,Correia Emmanuelle,Barry Alpha Amadou,Senina Nadège,Severi Gianluca,de Edelenyi Fabien Szabo,Allègre Julien,Druesne-Pecollo Nathalie,Esseddik Younes,Hercberg Serge,Touvier Mathilde,Charles Marie-Aline,Ancel Pierre-Yves,Benhammou Valérie,Ritmi Anass,Marchand Laetitia,Zaros Cecile,Lordmi Elodie,Candea Adriana,de Visme Sophie,Simeon Thierry,Thierry Xavier,Geay Bertrand,Dufourg Marie-Noelle,Milcent Karen,Lusivika-Nzinga Clovis,Pannetier Gregory,Lapidus Nathanael,Goderel Isabelle,Dorival Céline,Nicol Jérôme,Robineau Olivier,Carrat Fabrice,Lai Cindy,Belhadji Liza,Esperou Hélène,Couffin-Cadiergues Sandrine,Gagliolo Jean-Marie,Blanché Hélène,Sébaoun Jean-Marc,Beaudoin Jean-Christophe,Gressin Laetitia,Morel Valérie,Ouili Ouissam,Deleuze Jean-François,Priet Stéphane,Villarroel Paola Mariela Saba,Fourié Toscane,Ali Souand Mohamed,Amroun Abdenour,Seston Morgan,Ayhan Nazli,Pastorino Boris,de Lamballerie Xavier,de Lamballerie Xavier,Carrat Fabrice,Touvier Mathilde, , , , , , , , , , ,
Abstract
AbstractABO blood type has been reported as a potential factor influencing SARS-CoV-2 infection, but so far mostly in studies that involved small samples, selected population and/or used PCR test results. In contrast our study aimed to assess the association between ABO blood types and SARS-CoV-2 infection using seroprevalence data (independent of whether or not individuals had symptoms or sought for testing) in a large population-based sample. Our study included 67,340 French participants to the SAPRIS-SERO multi-cohort project. Anti-SARS-CoV-2 antibodies were detected using ELISA (targeting the proteins spike (S) and nucleocapsid (NP)) and seroneutralisation (SN) tests on dried blood spots collected in May–November 2020. Non-O individuals (and especially types A and AB) were more likely to bear anti SARS-CoV-2 antibodies (ELISA-S, 2964 positive cases: ORnon-Ovs.O = 1.09[1.01–1.17], ORAvs.O = 1.08[1.00–1.17]; ELISA-S/ELISA-NP/SN, 678 triple positive cases: ORnon-Ovs.O = 1.19 [1.02–1.39], ORAvs.O = 1.19[1.01–1.41], ORABvs.O = 1.43[1.01–2.03]). Hence, our results provided additional insights into the dynamic of SARS-CoV-2 infection, highlighting a higher susceptibility of infection for individuals of blood types A and AB and a lesser risk for blood type O.
Publisher
Springer Science and Business Media LLC