Allosteric Role of Substrate Occupancy Toward the Alignment of P-glycoprotein Nucleotide Binding Domains

Author:

Pan Lurong,Aller Stephen G.

Funder

U.S. Department of Health & Human Services | National Institutes of Health

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference65 articles.

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2. Linton, K. J. & Higgins, C. F. Structure and function of ABC transporters: the ATP switch provides flexible control (2007).

3. Rogan, A. M. et al. Reversal of adriamycin resistance by verapamil in human ovarian cancer. Science 224, 3 (1984).

4. Shen, D. W. et al. Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification. Science 232, 643 (1986).

5. Raviv, Y., Pollard, H. B., Bruggemann, E. P., Pastan, I. & Gottesman, M. M. Photosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells. J Biol Chem 265, 3975–3980 (1990).

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