Author:
Wang Na,Zhao Ting,Li Jiabei,Zeng Sisi,Wan Jixiang,Li Xuechao,Wang Fangjun
Abstract
AbstractOur objective was to observe the effects of extracorporeal circulation (ECC) with different time on platelet count in patients undergoing cardiac surgery. A total of 427 patients who underwent elective cardiac surgery under ECC in affiliated hospital of north Sichuan medical college from January 1, 2018 to July 31, 2021 were divided into three groups according to ECC time. We concluded that thrombocytopenia was common after ECC, maximum drop of the platelet counts after ECC was usually seen on the second day after ECC, and platelet counts started to recover on the fifth day after ECC. With the extension of ECC time, the drop in platelet counts is more pronounced, the volume of perioperative blood loss and blood products transfusion are more, and the recovery level and speed of platelet counts is lower.
Publisher
Springer Science and Business Media LLC
Reference22 articles.
1. Griffin, B. R. et al. Thrombocytopenia after cardiopulmonary bypass is associated with increased morbidity and mortality. Ann. Thorac. Surg. 110(1), 50–57 (2020).
2. Hamid, M., Akhtar, M. I., Naqvi, H. I. & Ahsan, K. Incidence and pattern of Thrombocytopenia in cardiac surgery patients. J. Pak. Med. Assoc. 67(7), 1019–1023 (2017).
3. Pouplard, C. et al. Changes in platelet count after cardiac surgery can effectively predict the development of pathogenic heparin-dependent antibodies. Br. J. Haematol. 128(6), 837–841 (2015).
4. Wahba, A., Rothe, G., Lodes, H., Barlage, S. & Schmitz, G. The influence of the duration of cardiopulmonary bypass on coagulation, fibrinolysis and platelet function. Thorac. Cardiovasc. Surg. 49(3), 153–156 (2001).
5. Gill, H., Wong, R. S. M. & Kwong, Y. L. From chronic immune thrombocytopenia to severe aplastic anemia: Recent insights into the evolution of eltrombopag. Ther. Adv. Hematol. 8(5), 159–174 (2017).
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献