Prophylactic Active Tau Immunization Leads to Sustained Reduction in Both Tau and Amyloid-β Pathologies in 3xTg Mice
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-17313-1.pdf
Reference57 articles.
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4. Congdon, E. E., Krishnaswamy, S. & Sigurdsson, E. M. Harnessing the immune system for treatment and detection of tau pathology. J. Alzheimers. Dis. 40, S113–S121 (2014).
5. Asuni, A. A., Boutajangout, A., Quartermain, D. & Sigurdsson, E. M. Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements. J. Neurosci. 27, 9115–9129 (2007).
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