Pharmacological use of a novel scaffold, anomeric N,N-diarylamino tetrahydropyran: molecular similarity search, chemocentric target profiling, and experimental evidence-Reference-Cited by-同舟云学术

Pharmacological use of a novel scaffold, anomeric N,N-diarylamino tetrahydropyran: molecular similarity search, chemocentric target profiling, and experimental evidence

Published:2017-10-02 Issue:1 Volume:7 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Venkanna Arramshetti,Kwon Oh Wook,Afzal Sualiha,Jang Cheongyun,Cho Kyo Hee,Yadav Dharmendra K.,Kim Kang,Park Hyeung-geun,Chun Kwang-Hoon,Kim Sun Yeou,Kim Mi-hyun^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-017-12082-3.pdf

Reference51 articles.

1. ‘Diversity-oriented synthesis (DOS)’: M. D. Burke, E. M. Berger, S. L. Schreiber, Generating diverse skeletons of small molecules combinatorially, Science, 302, 613–618 (2003).

2. ‘Biology-oriented synthesis (BIOS)’: S. Wetzel, R. S. Bon, K. Kumar, H. Waldmann, Biology-oriented synthesis, Angew. Chem. Int. Ed., 50, 10800–1082 (2011).

3. ‘Function-oriented synthesis (FOS)’: P. A. Wender, V. A. Verma, T. J. Paxton, T. H. Pillow, Function-oriented synthesis, step economy, and drug design: Acc. Chem. Res., 41, 40–49 (2008).

4. Shelat, A. A. & Guy, R. K. Scaffold composition and biological relevance of screening libraries. Nature Chemical Biology 3, 442–446 (2007).

5. Schuffenhauer, A. & Jacoby, E. Annotating and mining the ligand-target chemogenomics knowledge space. Drug. Discov. Today.: BIOSILICO 2, 190–200 (2004).

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