Structural basis of translation inhibition by cadazolid, a novel quinoxolidinone antibiotic
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-019-42155-4.pdf
Reference52 articles.
1. Wilson, D. N. The A-Z of bacterial translation inhibitors. Crit Rev Biochem Mol Biol 44, 393–433, https://doi.org/10.3109/10409230903307311 (2009).
2. Klinge, S., Voigts-Hoffmann, F., Leibundgut, M. & Ban, N. Atomic structures of the eukaryotic ribosome. Trends Biochem Sci 37, 189–198, https://doi.org/10.1016/j.tibs.2012.02.007 (2012).
3. Wilson, D. N. Ribosome-targeting antibiotics and mechanisms of bacterial resistance. Nat Rev Microbiol 12, 35–48, https://doi.org/10.1038/nrmicro3155 (2014).
4. Wilson, D. N. et al. The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning. Proc Natl Acad Sci USA 105, 13339–13344, https://doi.org/10.1073/pnas.0804276105 (2008).
5. Lin, J., Zhou, D., Steitz, T. A., Polikanov, Y. S. & Gagnon, M. G. Ribosome-Targeting Antibiotics: Modes of Action, Mechanisms of Resistance, and Implications for Drug Design. Annu Rev Biochem 87, 451–478, https://doi.org/10.1146/annurev-biochem-062917-011942 (2018).
Cited by 20 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Discovery and Structure–Activity Relationship of Cadazolid: A First-In-Class Quinoxolidinone Antibiotic for the Treatment of Clostridioides difficile Infection;Journal of Medicinal Chemistry;2024-05-16
2. Identification of CH2-linked quinolone-aminopyrimidine hybrids as potent anti-MRSA agents: Low resistance potential and lack of cross-resistance with fluoroquinolone antibiotics;European Journal of Medicinal Chemistry;2024-05
3. Simultaneous Determination of Contezolid and Its Metabolite M2 in Human Plasma and Cerebrospinal Fluid by Ultra-High-Performance Liquid Chromatography – Tandem Mass Spectrometry (UHPLC-MS/MS);Analytical Letters;2023-11-08
4. Hybridization of antimicrobial oxazolidinones with commercial drugs: A fight against the “superbugs”;Drug Development Research;2023-08-15
5. Bifunctional antibiotic hybrids: A review of clinical candidates;Frontiers in Pharmacology;2023-06-12
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3