Abstract
AbstractA new photoionization scheme accessible by Rhodamine dye lasers is proposed for the isotope separation of 176Lu.$$5d6s^{2}\,{^{2}D_{{3/2}}} (0.0\, {\text{cm}}^{{ - 1}} )\mathop{\longrightarrow}\limits^{{573.8130\, {\text{nm}}}}5d6s6p\,{^{4}F_{{3/2}}^{o}} \left( {17427.28\, {\text{cm}}^{{ - 1}} } \right)\mathop{\longrightarrow}\limits^{{560.3114\, {\text{nm}}}}$$
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$$6s{6p}^{2}\,{^{4}{P}_{5/2}}\left(35274.5 \,{\text{cm}}^{-1}\right){\to } Autoionization\, State {\to }{Lu}^{+}$$
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Optimum conditions for the laser isotope separation have been theoretically computed and compared with the previously reported work. The enrichment of ~ 63% can be obtained with > 22 mg/h production rate even when broadband lasers with bandwidth of 500 MHz are employed for the two step excitation. The simplified system requirements for the photoionization scheme combined with a high production rate of 176Lu than previously reported is expected to reduce the global shortage of 176Lu isotope for medical applications.
Publisher
Springer Science and Business Media LLC
Reference21 articles.
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2. Cohen, K. & Murphy, G. M. The theory of isotope separation as applied to the large scale production of U235 (Mcgraw-Hill Book Company Inc, 1951).
3. Ignac, F. Atlas of clinical nuclear medicine 3rd edn. (CRC Press, 2014).
4. Dash, A., Raghavan, M., Pillai, A. & Knapp, F. F. Jr. Production of 177Lu for targeted radionuclide therapy: available options. Nucl. Med. Mol. Imaging 49, 85–107 (2015).
5. Dyachkov, A. B. et al. Selective photoionisation of lutetium isotopes. Quantum Electron. 42, 953–956 (2012).
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