Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo

Author:

Komar Hannah M.,Serpa Gregory,Kerscher Claire,Schwoegl Erin,Mace Thomas A.,Jin Ming,Yang Ming-Chen,Chen Ching-Shih,Bloomston Mark,Ostrowski Michael C.,Hart Phil A.,Conwell Darwin L.,Lesinski Gregory B.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Reference57 articles.

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2. Ewald, N. & Hardt, P. D. Diagnosis and treatment of diabetes mellitus in chronic pancreatitis. World J Gastroenterol 19, 7276–7281, doi: 10.3748/wjg.v19.i42.7276 (2013).

3. Pezzilli, R. Chronic pancreatitis: maldigestion, intestinal ecology and intestinal inflammation. World J Gastroenterol 15, 1673–1676 (2009).

4. Haas, S., Krins, S., Knauerhase, A. & Löhr, M. Altered bone metabolism and bone density in patients with chronic pancreatitis and pancreatic exocrine insufficiency. JOP 16, 58–62 (2015).

5. Lankisch, P. G., Löhr-Happe, A., Otto, J. & Creutzfeldt, W. Natural course in chronic pancreatitis. Pain, exocrine and endocrine pancreatic insufficiency and prognosis of the disease. Digestion 54, 148–155 (1993).

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